1<!DOCTYPE html>
2
3Anonymous
4/bestp
5/bestp/domrep.nsf
6CFE5CC1F56E60636002589AA00267B5F
8
9
10
11
12
13
140
15
16
17/bestp/domrep.nsf/products/case-study-how-horizon-therapeutics-created-ophthalmic-blockbuster-rare-disease-autoimmune-area-thyroid-eye-disease
18
19
2044.200.82.149
21
22
23best-in-class.com
24/bestp/domrep.nsf
25BMR




» Products & Services » » Product Launch » Product Launch Excellence

Case Study: How Horizon Therapeutics Created an Ophthalmic Blockbuster in a Rare Disease Autoimmune Area for Thyroid Eye Disease

ID: PSM-389


Features:

44 Info Graphics

13 Data Graphics

230+ Metrics

9 Narratives


Pages: 70


Published: 2023


Delivery Format: Shipped


 

License Options:


Buy Now

 

919-403-0251

  • STUDY OVERVIEW
  • BENCHMARK CLASS
  • STUDY SNAPSHOT
  • KEY FINDINGS
  • VIEW TOC AND LIST OF EXHIBITS
In January 2020, Horizon Therapeutics achieved a significant milestone with the FDA approval of Tepezza (teprotumumab-trbw), the first IGF-1R blocker for patients with thyroid eye disease (TED). While its closest competitors, Immunovant and Novartis, are still awaiting Phase 3 trial completions anticipated in early 2025, Tepezza's first-mover advantage propelled it to surpass the $1 billion mark within just 18 months of its launch.

A detailed case study of Tepezza unveils valuable market insights, showcasing the education campaigns, patient support initiatives, innovative partnerships, and competitive resourcing tactics implemented by Horizon Therapeutics. These strategic approaches played a pivotal role in creating an ophthalmic blockbuster in the rare disease autoimmune area of thyroid eye disease. This comprehensive case study conducted by Best Practices, LLC meticulously examines the launch, market-entry strategies, and execution of Horizon for Tepezza, providing valuable lessons for industry stakeholders.

Industries Profiled:
Biotech; Pharmaceutical


Companies Profiled:
Amgen; Horizon Therapeutics

Study Snapshot

Best Practices, LLC conducted extensive secondary research to examine how Horizon Therapeutics created an ophthalmic blockbuster in a rare disease autoimmune area.

Key Findings

Select key insights uncovered from this report are noted below. Detailed findings are available in the full report.

  • Patient Support Program: Horizon has introduced Patient Access Liaisons who team up with patients and their HCPs to support them throughout the treatment process, including providing assistance with payers.
  • The Pandemic Shuts 77% Ophthalmologist Offices:
    • Effect- Tepezza commercialization and administration was hampered.
    • How was it Fixed?- Network of 1,000 infusion centers developed; doctors approached digitally by Tepezza reps; digital marketing and TV advertising.
    • Impact in 2020- 1 Million visits recorded by Tepezza and TED websites; $820M annual revenue recorded by Tepezza (Exceeded projected revenue by 20x)
Table of Contents

Sr. No.
Topic
Slide No.
I.
Introduction to Horizon Therapeutics and Tepezza for TEDPg. 3-13
II.
Tepezza’s Progression Since LaunchPg. 14-19
III.
Disease Awareness, Patient Education, and Symptom IdentificationPg. 20-30
IV.
Patient Access and Support Help TED Patients Navigate Authorization, Reimbursement, and Start of TreatmentPg. 31-35
V.
D2C Education & Communications: A Cornerstone of Tepezza’s Education CampaignPg. 36-39
VI.
Roadblocks and Resolutions in Tepezza’s JourneyPg. 40-45
VII.
Partnerships: Tepezza Leveraged Strengths of Partners to Enter MarketPg. 46-52
VIII.
Financial Health of Horizon Since the Release of TepezzaPg. 53-61
IX.
Tepezza Staffing Analysis: Examining the Talent and Resources to Compete in the TED MarketPg. 62-67
X.
Summary Lessons Learned from Tepezza’s Successful Market EntryPg. 68-69